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A warm welcome to our new PhD students!
We are very excited to welcome our incoming class of 2023 into the Berkeley Neuroscience community and to support them in their scientific development. If you see them around campus, be sure to give them a wave!
Bottom row, left to right: Haidyn Bulen,...Read more about A warm welcome to our new PhD students!
Postdoc Mark Plitt awarded Jane Coffin Childs Fund for Medical Research fellowship
Congratulations to Mark Plitt, a postdoc in the lab of Yvette Fisher!Read more about Postdoc Mark Plitt awarded Jane Coffin Childs Fund for Medical Research fellowship
Marla Feller elected to National Academy of Sciences
Congratulations to Marla Feller!Read more about Marla Feller elected to National Academy of Sciences
Yvette Fisher receives AAA C.J. Herrick Award in Neuroanatomy
Adolescent Development of Biological Rhythms in Female Rats: Estradiol Dependence and Effects of Combined Contraceptives
Front Physiol. 2021 Nov 5;12:752363. doi: 10.3389/fphys.2021.752363. eCollection 2021.
ABSTRACT
Adolescence is a period of continuous development, including the maturation of endogenous rhythms across systems and timescales. Although, these dynamic changes are well-recognized
...Read more about Adolescent Development of Biological Rhythms in Female Rats: Estradiol Dependence and Effects of Combined ContraceptivesThe Role of Executive Function in Shaping Reinforcement Learning
Curr Opin Behav Sci. 2021 Apr;38:66-73. doi: 10.1016/j.cobeha.2020.10.003. Epub 2020 Nov 14.
ABSTRACT
Reinforcement learning (RL) models have advanced our understanding of how animals learn and make decisions, and how the brain supports some aspects of learning. However, the
...Read more about The Role of Executive Function in Shaping Reinforcement LearningMüller Glia in Retinal Development: From Specification to Circuit Integration
Front Neural Circuits. 2022 Feb 4;15:815923. doi: 10.3389/fncir.2021.815923. eCollection 2021.
ABSTRACT
Müller glia of the retina share many features with astroglia located throughout the brain including maintenance of homeostasis, modulation of neurotransmitter spillover,
...Read more about Müller Glia in Retinal Development: From Specification to Circuit IntegrationSex-specific genetic predictors of memory performance
Alzheimers Dement. 2021 Dec;17 Suppl 3:e056083. doi: 10.1002/alz.056083.
ABSTRACT
BACKGROUND: There are notable sex differences in the clinical manifestation of Alzheimer's disease (AD), including differences in baseline and longitudinal changes in memory performance. However
...Read more about Sex-specific genetic predictors of memory performanceSex differences in the genetic architecture underlying resilience in AD
Alzheimers Dement. 2021 Dec;17 Suppl 3:e055010. doi: 10.1002/alz.055010.
ABSTRACT
BACKGROUND: Approximately 30% of older adults are cognitively normal at death despite presence of Alzheimer's disease (AD) neuropathology at autopsy. Studying these "resilient" individuals may
...Read more about Sex differences in the genetic architecture underlying resilience in ADLongitudinal Early-onset Alzheimer's Disease Study (LEADS) genetic screening: Initial results
Alzheimers Dement. 2021 Dec;17 Suppl 3:e056493. doi: 10.1002/alz.056493.
ABSTRACT
BACKGROUND: The Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) aims to enroll and study participants with sporadic early-onset Alzheimer's disease (EOAD) or early-onset non-Alzheimer
...Read more about Longitudinal Early-onset Alzheimer's Disease Study (LEADS) genetic screening: Initial resultsLong-Term Motor Learning in the "Wild" With High Volume Video Game Data
Front Hum Neurosci. 2021 Dec 20;15:777779. doi: 10.3389/fnhum.2021.777779. eCollection 2021.
ABSTRACT
Motor learning occurs over long periods of practice during which motor acuity, the ability to execute actions more accurately, precisely, and in less time, improves.
...Read more about Long-Term Motor Learning in the "Wild" With High Volume Video Game DataWhat do Reinforcement Learning Models Measure? Interpreting Model Parameters in Cognition and Neuroscience
Curr Opin Behav Sci. 2021 Oct;41:128-137. doi: 10.1016/j.cobeha.2021.06.004. Epub 2021 Jul 3.
ABSTRACT
Reinforcement learning (RL) is a concept that has been invaluable to fields including machine learning, neuroscience, and cognitive science. However, what RL entails differs
...Read more about What do Reinforcement Learning Models Measure? Interpreting Model Parameters in Cognition and NeuroscienceA silicon-rhodamine chemical-genetic hybrid for far red voltage imaging from defined neurons in brain slice
RSC Chem Biol. 2021 Sep 29;2(6):1594-1599. doi: 10.1039/d1cb00156f. eCollection 2021 Dec 2.
ABSTRACT
We describe the design, synthesis, and application of voltage-sensitive silicon rhodamines. Based on the Berkeley Red Sensor of Transmembrane potential, or BeRST, scaffold,
...Read more about A silicon-rhodamine chemical-genetic hybrid for far red voltage imaging from defined neurons in brain sliceDistinct Factors Drive the Spatiotemporal Progression of Tau Pathology in Older Adults
J Neurosci. 2022 Feb 16;42(7):1352-1361. doi: 10.1523/JNEUROSCI.1601-21.2021. Epub 2021 Dec 29.
ABSTRACT
Mechanisms underlying the initial accumulation of tau pathology across the human brain are largely unknown. We examined whether baseline factors including age, amyloid-β (
...Read more about Distinct Factors Drive the Spatiotemporal Progression of Tau Pathology in Older AdultsCognitive strategies shift information from single neurons to populations in prefrontal cortex
Neuron. 2022 Feb 16;110(4):709-721.e4. doi: 10.1016/j.neuron.2021.11.021. Epub 2021 Dec 20.
ABSTRACT
Neurons in primate lateral prefrontal cortex (LPFC) play a critical role in working memory (WM) and cognitive strategies. Consistent with adaptive coding models, responses of
...Read more about Cognitive strategies shift information from single neurons to populations in prefrontal cortexThe retrocalcarine sulcus maps different retinotopic representations in macaques and humans
Brain Struct Funct. 2022 May;227(4):1227-1245. doi: 10.1007/s00429-021-02427-0. Epub 2021 Dec 17.
ABSTRACT
Primate cerebral cortex is highly convoluted with much of the cortical surface buried in sulcal folds. The origins of cortical folding and its functional relevance have
...Read more about The retrocalcarine sulcus maps different retinotopic representations in macaques and humansRegional gray matter oligodendrocyte- and myelin-related measures are associated with differential susceptibility to stress-induced behavior in rats and humans
Transl Psychiatry. 2021 Dec 13;11(1):631. doi: 10.1038/s41398-021-01745-5.
ABSTRACT
Individual reactions to traumatic stress vary dramatically, yet the biological basis of this variation remains poorly understood. Recent studies demonstrate the surprising plasticity of
...Read more about Regional gray matter oligodendrocyte- and myelin-related measures are associated with differential susceptibility to stress-induced behavior in rats and humansStructural basis for pH gating of the two-pore domain K<sup>+/sup> channel TASK2
Nature. 2020 Sep 30. doi: 10.1038/s41586-020-2770-2. Online ahead of print.
ABSTRACT
TASK2 (also known as KCNK5) channels generate pH-gated leak-type K+ currents to control cellular electrical excitability1-3. TASK2 is involved in the regulation of
...Read more about Structural basis for pH gating of the two-pore domain K+/sup> channel TASK2Magnetotactic bacteria accumulate a large pool of iron distinct from their magnetite crystals
Appl Environ Microbiol. 2020 Sep 4:AEM.01278-20. doi: 10.1128/AEM.01278-20. Online ahead of print.
ABSTRACT
Magnetotactic bacteria (MTB) are ubiquitous aquatic microorganisms that form intracellular nanoparticles of magnetite (Fe3O4) or greigite (Fe
...Read more about Magnetotactic bacteria accumulate a large pool of iron distinct from their magnetite crystalsSleep Disturbance Forecasts β-Amyloid Accumulation across Subsequent Years
Curr Biol. 2020 Aug 28:S0960-9822(20)31171-4. doi: 10.1016/j.cub.2020.08.017. Online ahead of print.
ABSTRACT
Experimental sleep-wake disruption in rodents and humans causally modulates β-amyloid (Aβ) dynamics (e.g., [1-3]). This leads to the hypothesis that, beyond cross-
...Read more about Sleep Disturbance Forecasts β-Amyloid Accumulation across Subsequent Years- « first News
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